Electrical Synapse Impulses can be regenerated without interruption in adjacent cells Gap junctions Adjacent cells electrically Cytoplasm s Plasma coupled through a MEmbrane of one cell channe Plasma Two cells, membrane inter- of adja Each gap junction is connected< cell/acent y gap composed of 12 connexin junctions Connexin proteins proteins Cytoplasm forming gap unctions · Examples: Smooth and cardiac muscles, brain, and glial cells
Electrical Synapse • Impulses can be regenerated without interruption in adjacent cells. • Gap junctions: – Adjacent cells electrically coupled through a channel. – Each gap junction is composed of 12 connexin proteins. • Examples: – Smooth and cardiac muscles, brain, and glial cells
Electrical Synapses Electric current flow- communication takes place by flow of electric current directly from one cell2 neuron to the other crop .No synaptic cleft or vesicles cell membranes in direct contact communication not cytoplasm Iong and Charnel forned polarized- electric current ena.1 noleculemby pores in can flow between cells in either direction
•Electric current flowcommunication takes place by flow of electric current directly from one neuron to the other •No synaptic cleft or vesicles cell membranes in direct contact •Communication not polarized- electric current can flow between cells in either direction Electrical Synapses
Microtubule Presvnaptic Presynaptic neuron Cytoplasm neuron Synaptic vesicle Mitochondrion ○○ Gar neuron junction lons flow through gap junction channels Synaptic Neurotransmitter released Presynaptic membrane icle fusing Presynaptic membrane S cleft 。 Postsynaptic neurotransmitter membrane Gap junction channels Postsynaptic receptor lons flow through membrane postsynaptic channels Electrical Synapse Chemical synapse Purves 2001
Electrical Synapse Chemical Synapse Purves, 2001
I The Chemical Synapse and Signal Transmission
I The Chemical Synapse and Signal Transmission
The chemical synapse is a specialized junction that transfers nerve impulse information from a pre synaptic membrane to a postsynaptic membrane using neurotransmitters and enzymes Cell body Dendrites Axodendritic Axosomatic synapses synapses Axoaxonal synapses Axon D BENJAMIN/CUMMINGS
• The chemical synapse is a specialized junction that transfers nerve impulse information from a pre synaptic membrane to a postsynaptic membrane using neurotransmitters and enzymes