EDIARD'SSYNDROMIE Trisomy 18 Dania m. Jacob(12307076020)
Dania M. Jacob (12301016020) 1
EDWARDS SYDROME Trisomy 18 is the second most common trisomy and occurs when a baby has three of the eighteenth chromosome /t is this extra genetic material that causes the problems associated with Trisomy 18 Edwards syndrome affects around 7 i3,000, but only7i5,000 6 000 live births b(72301076020)
Edward’s syndromE • Trisomy 18 is the second most common trisomy and occurs when a baby has three of the eighteenth chromosome. • It is this extra genetic material that causes the problems associated with Trisomy 18. • Edward's syndrome affects around 1 in 3,000, but only 1 in 5,000 – 6,000 live births. Dania M. Jacob (12301016020) 2
Karyotype From a Female With Edwards Syndrome (47, XX, +18) 2 16 20 2122X dG Clinical Tools,Inc b(72301076020)
Dania M. Jacob (12301016020) 3
CAUSES EDWYARD'S Trisomy 78 is caused by a miss r disjuncture during mitosis Parents have done nothing before or during pregnancy to cause this ah/30mh加 hEir chile b(72301076020)
causEs Edward’s • Trisomy 18 is caused by a missdisjuncture during mitosis. • Parents have done nothing before or during pregnancy to cause this disorder in their child. Dania M. Jacob (12301016020) 4
TYPES OFEDWARDS With each type, there is a range of possibilities Some children are medically fragile While others thrive Some children walk while others are confined to wheelchairs ab(12307076020)
TypEs of Edward’s • With each type, there is a range of possibilities. • Some children are medically fragile while others thrive • Some children walk while others are confined to wheelchairs. Dania M. Jacob (12301016020) 5