Medical Genetics Target cells such as the patient's liver or lung cells are infected with the viral vector the vector then unloads its genetic material containing the therapeutic human gene into the target cell
Medical Genetics Target cells such as the patient's liver or lung cells are infected with the viral vector. The vector then unloads its genetic material containing the therapeutic human gene into the target cell
Medical Genetics The generation of a functional protein product from the therapeutic gene restores the target cell to a normal state
Medical Genetics The generation of a functional protein product from the therapeutic gene restores the target cell to a normal state
Medical Genetics DNA 2 chromosome ( ucleus CfIDTOsome therapeutic DNA ) target To reverse disease caused by genetic damage, researchers isolate normal DNa and package it into a vector, a molecular delivery truck usually made from a disabled virus. Doctors then infect a target cell -usually from a tissue affected by the illness such as liver or lung cells--with the vector. The vector unloads its dNa cargo, which then begins producing the missing protein and restores the cell to normal
Medical Genetics To reverse disease caused by genetic damage, researchers isolate normal DNA and package it into a vector, a molecular delivery truck usually made from a disabled virus. Doctors then infect a target cell —usually from a tissue affected by the illness, such as liver or lung cells—with the vector. The vector unloads its DNA cargo, which then begins producing the missing protein and restores the cell to normal
Medical Genetics A. Some of the different types of viruses used as gene therapy vectors (1) Retroviruses a class of viruses that can create double-stranded dna copies of their rna genomes. These copies of its genome can be integrated into the chromosomes of host cells. Human immunodeficiency virus HIV is a retrovirus
Medical Genetics A. Some of the different types of viruses used as gene therapy vectors (1) Retroviruses A class of viruses that can create double-stranded DNA copies of their RNA genomes. These copies of its genome can be integrated into the chromosomes of host cells. Human immunodeficiency virus (HIV) is a retrovirus
Medical Genetics (2)Adenoviruses a class of viruses with double-stranded dna genomes that cause respiratory, intestinal, and eye infections in humans. The virus that causes the common cold is an adenovirus (Adeno-associated viruses A class of small, single-stranded DNA viruses that can insert their genetic material at a specific site on chromosome 19 (4)Herpes simplex viruses a class of double-stranded dna viruses that infect a particular cell type, neurons. Herpes simplex virus type 1 is a common human pathogen that causes cold sores
Medical Genetics (2)Adenoviruses A class of viruses with double-stranded DNA genomes that cause respiratory, intestinal, and eye infections in humans. The virus that causes the common cold is an adenovirus. (3)Adeno-associated viruses A class of small, single-stranded DNA viruses that can insert their genetic material at a specific site on chromosome 19. (4)Herpes simplex viruses A class of double-stranded DNA viruses that infect a particular cell type, neurons. Herpes simplex virus type 1 is a common human pathogen that causes cold sores