消去的取向:(查依采夫规则) HSO CH3CH2CH-C386°C CH3=CHCH3+ CH3CH2 CH=CH2 OH 80% 20% 也有重排(E1历程) CH3 3 CH3 CH3C—CH-CH3一 Ch3 C-CH=CH Ch,oh 3 CH3 70% 30% Organic chem
Organic Chem 消去的取向：(查依采夫规则) 也有重排（E1历程） CH3CH2 CH OH CH3 H2 SO4 86C CH3CH CHCH3 + CH3CH2CH CH2 80% 20% CH3 C CH3 CH3 CH OH CH3 C C H3 C H3 C CH3 CH3 H+ CH3 C CH3 CH3 + CH CH2 70% 30%
4.醇的氧化脱氢反应: 氧化:1 K2 CrOw RCHOH RCH— RCOOH H OH KCro1R-C—R R-CH-R 3°一般不反应, 条件激烈时,氧化同时裂解: CH3 CH3 C-OH+ HNO3 C=CH H2O H2C O CO2+H2O+ CH3COOH CH2-C-CH3 +H2O+ CO2 Organic chem
Organic Chem 4. 醇的氧化脱氢反应： 氧化： 3º 一般不反应， 条件激烈时，氧化同时裂解： 1º 2º RCH2OH H + K2CrO7 RCHO RCOOH R CH OH R' H + K2CrO7 R C O R' CH3 C CH3 CH3 OH H+ C CH H3C H3C [O] CH3 C O CH3 + H2O + CO2 [O] CH3COOH --H2O + HNO3 CO2 + H2O +