clinical features ◆ chron1c ☆ acute arpa 11 or cAlgon、 jaundice hyperpyrexia、 splenomegaly sore walst cHolelithiasis hEmoglobinuria cRaplastic crisis c& jaundice anaemia
clinical features ❖chronic pallor 、 jaundice 、 splenomegaly cholelithiasis aplastic crisis ❖acute algor、 hyperpyrexia、 sore waist hemoglobinuria jaundice、 anaemia
laboratory examination Increased rbc destruction 令 Reduced RBC life span . Indirect hyperbilirubinemia Erythroid hyperplasia 令 Reticulocytosis Erythroblasts, anisopoikilocytosis spherocytes in blood smear Erythroid hyperplasia in bone marrow
laboratory examination ❖ Increased RBC destruction ❖ Reduced RBC life span ❖ Indirect hyperbilirubinemia ❖ Erythroid hyperplasia ❖ Reticulocytosis ❖ Erythroblasts, anisopoikilocytosis, spherocytes in blood smear ❖ Erythroid hyperplasia in bone marrow
2 oooo
diagnosis and differential diagnosis 冷 hemolysis or not? 冷 type of hemolysis ☆ another anemia o another jaundice with anemia s another jaundice without anemia?
diagnosis and differential diagnosis ❖hemolysis or not? ❖type of hemolysis ❖another anemia? ❖another jaundice with anemia? ❖another jaundice without anemia?