the bigger problem is M protein may have cross antigenecity with some of human tissue such as endocardium and glomerular basement membrane
M protein may have cross antigenecity with some of human tissue such as endocardium and glomerular basement membrane. the bigger problem is…
type III hypersensitivity (most) type II hypersensitivity M protein-Ab immune complex common Ag deposition on glomerular basement membrane cross reacts with glomerular basement membrane activation of complement tissue destruction tissue destruction
type III hypersensitivity (most) M protein-Ab immune complex deposition on glomerular basement membrane activation of complement tissue destruction type II hypersensitivity common Ag cross reacts with glomerular basement membrane tissue destruction