1.肌动蛋白单体结合蛋白 单体隔离 胸腺素β4 前纤维蛋白
1. 肌动蛋白单体结合蛋白
2.成核蛋白 activating factor minus plus other proteins end end Arp3 inactive Arp2 actin nucleated actin filament ARP complex active ARP complex monomers (+end Arp3 Conformational 70°(+)end Arp2 change -)end WASp activation domain (-)end Figure 17-15a Molecular Cell Biology,Sixth Edition o2008 W.H.Freeman and Company
2. 成核蛋白
3.加帽蛋白 Listeria ActA Actin assembly (+)end ,加帽蛋白 Arp2/3 complex Capping protein 肌动蛋白 Cofilin 0● Arp2 Arp3 Arp2/3复合物 Actin disassembly (-end Figure 17-17c Moleculor Cell Biology.Sixth Edition 2008 W.H.Freeman and Company
3.加帽蛋白
4.交联蛋白 actin filaments and actin filaments and o-actinin fimbrin filamin C202线P dimer 心 Q20000 50nm contractile bundle parallel bundle loose packing allows myosin-ll tight packing prevents myosin-ll (A) to enter bundle from entering bundle 50 nm Figure 16-49a 16-51 Molecular Biology of the Cell(Garland Science 2008)
4. 交联蛋白 Figure 16-49a 16-51 Molecular Biology of the Cell (© Garland Science 2008)
5.割断及解聚蛋白 Fragmenting Filamin (ADF/Cofilin) Action of gelsolin in severing actin filaments http://www.ncbi.nlm.nih.gov/books/NBK21594/
5. 割断及解聚蛋白 Action of gelsolin in severing actin filaments http://www.ncbi.nlm.nih.gov/books/NBK21594/