Outside Inside
1.3.8 Peripheral proteins can be released from membranes by relativel mild treatments and once released are generally water soluble 1.3.9 Membrane proteins covalently attached to lipids of several kinds are anchored to the lipid bilayer(e. g, fatty acyl chain, farnesyl chain and others)
1.3.8 Peripheral proteins can be released from membranes by relatively mild treatments and once released are generally water soluble. 1.3.9 Membrane proteins covalently attached to lipids of several kinds are anchored to the lipid bilayer (e.g., fatty acyl chain, farnesyl chain and others)
protein change in pH; chelating agent urea: CO phospholipase C Lipid-linked protein Protein-glycan Integral protein (hydrophobic domain coated with detergent)
table 12-1 Major Components of Plasma Membranes in Various Organisms Components(% by weight) rotein Phospholipid Sterol Sterol type Other lipids Human myelin sheath 19 Cholesterol Galactolipids. plasmalogens Mouse liver 45 27 25 Cholesterol Maize leaf 47 Sitosterol Galactolipids Yeast 265 744 Ergosterol Triacylglycerols, steryl esters Paramecium (ciliated protist Stigmasterol E. coli
Plasma Inner mitochondrial Outer E mitochondrial al ear Rough ER Smooth ER golgi 40 60 100 Percent membrane lipid Cholesterol Sphingolipids Cardiolipin Phosphatidylcholine □ Minor lipids口 Phosphatidylethanolamine