Development ofCardiovascularSystem
Development of Cardiovascula iovascular ovascular System
Overview.DerivedfromMesodermStartsinthe3rdweek. Some changestakeplace at birth in the1st postnatal month
Overview • Derived from Mesoderm • Starts in the 3rd week • Some changes take place at birth in the 1st postnatal month
Learning aimsUnderstand primitive cardiovascular systemDescribe development of heart-Outerformation of theheart-Partitioning of the heart chambersDescribecirculationbefore andafterbirthDescribecongenitalmalformation
Learning aims • Understand primitive cardiovascular system • Describe development of heart – Outer formation of the heart – Partitioning of the heart chambers • Describe circulation before and after birth • Describe congenital malformation
1. Primitive cardiovascular system1.1 extraembryonic blood vessels:VillYolk sac (mesoderm)Amniotic caviAmniobloodislandsBloodvesselHeartAllantoisPericEndotheliaprimitive blood cellscavityConnectingstalk(peripheral)(central)YollChorionBloodislandBloodvesselEndothelialLumen primiliveBloodPrimitivecellbloodvesselMesenchyme cellsvesselsblood cellsistandbloodcellvessels netangiogenesis
1. Primitive cardiovascular system 1.1 extraembryonic blood vessels: Yolk sac (mesoderm) blood islands Endothelia primitive blood cells angiogenesis (peripheral) (central) vessels blood cells vessels net
1.2 intraembryonic blood vessels:3.Cardiac anlage5.Anlage of the dorsal8aortaO106.Umbilicalvein7.Umbilicalartery8.(Anlageoftheextraembryonic)arterial12vessels1310.Anlage of the14(extraembryonic)venousvessels
1.2 intraembryonic blood vessels: 3.Cardiac anlage 5.Anlage of the dorsal aorta 6.Umbilical vein 7.Umbilical artery 8.( Anlage of the extraembryonic) arterial vessels 10.Anlage of the (extraembryonic) venous vessels