Pathogenesy of PU--Helicobacter pylori 浙医一院 The colonization factor of hp bostrychoid, have flegalla urase especial adherence factor Invasive factor urase ammoniacal toxicity Vac A Cag A and phosphatidase Al chemotact and activate inflammatory cell antigen imitate Two theory hypothesis of leaking roof gastrin-link hypothesis d cell& somatostatin
The colonization factor of HP bostrychoid,have flegalla urase especial adherence factor Invasive factor urase ammoniacal toxicity Vac A, Cag A and phosphatidase A1 chemotact and activate inflammatory cell antigen imitate Two theory: hypothesis of leaking roof gastrin-link hypothesis D cell & somatostatin Pathogenesy of PU—Helicobacter Pylori
Infection with H. pylori results in an acute inflammatory reaction 浙医一院 Epithelial cell radicals flumorph
IL-8 Proteolytic enzymes O2 radicals Infection with H. pylori results in an acute inflammatory reaction Epithelial cell Polymorph
Increasing proportion of H pylori-negative ulcers 1995-2000 1995 2000 13% 33% 87% 67% H pylori-negative gastroduodenal ulcers H pylori-positive gastroduodenal ulcers Juhasz, Gut 2001: 49: A64
1995 2000 H. pylori-positive gastroduodenal ulcers 13% 87% 33% 67% H. pylori-negative gastroduodenal ulcers Juhasz, Gut 2001; 49: A64. Increasing proportion of H. pylori-negative ulcers 1995–2000