浙医一院 A cid, pepsine Balance in attack d
Balance in attack and defence Acid, pepsine
Mucosal damage 浙医一院 Pathogenesy of pu .Acid and pepsine .Helicobacter pylori NSAIDs .Motility disturbance Stress .Systemic inflammatory disorders . schemia Hypergastrinemic Syndromes .Hyperhistaminic syndromes Anastomotic or marginal Ulceration Alcohol Tobacco
Mucosal damage Pathogenesy of PU •Acid and Pepsine •Helicobacter pylori •NSAIDs •Motility disturbance •Stress •Systemic inflammatory disorders •Ischemia •Hypergastrinemic Syndromes •Hyperhistaminic Syndromes •Anastomotic or marginal Ulceration •Alcohol •Tobacco
浙医一院 Pathogenesy of PU--Acid Pepsine Pepsine Maxim um activity of enzyme%) rely on Acid o no acid no ulcer 60 parietal cell mass parietal sensibility feedback suppression 1 2 3 Gastric fluid pH e vagal tone
Pathogenesy of PU—Acid & Pepsine 0 20 40 60 80 100 Maximum activity of enzyme(%) 1 2 3 Gastric fluid pH 4 2 4 Pepsine rely on Acid no acid,no ulcer parietal cell mass parietal sensibility feedback suppression vagal tone
Pathogenesy ofpu 浙医一院 -Helicobacter pylori Biology abostrychoid,have flegalla, microamount requirement of oxygen urase urea NH3 oVac A cag A Evidence-based medicine high positive rate of HP in PU the eradication of Hp facilitate the healing of PU the eradication of Hp degrades the recurrence of PU
Biology bostrychoid,have flegalla, microamount requirement of oxygen urase: urea NH3 Vac A, Cag A Evidence-based medicine high positive rate of HP in PU the eradication of Hp facilitate the healing of PU the eradication of Hp degrades the recurrence of PU Pathogenesy of PU —Helicobacter Pylori
The Nobel prize in physiology or Medicine 2005 for their discovery of the bacterium Heficobacter pylori and its role in gastritis and peptic ulcer disease Barry J. Marshal 1. Robin warren ①1/2 of the prize ①1/2 of the prize Australia Australia NHMRC Helicobacter pylori Research Laboratory, QEII Perth, Australia Medical Centre: University of Western Australia Nedlands, Australia b,19512005年10月 b.1937
2005年10月