Germ cell and fertilization Germ cell spermatozoon and ovum 1. spermatozoon Capacitation: In female reproductive tract, the sperms were enabled to bind to the zona pellucida receptors removal of glycoproteins(decapacitation factor which cover the sperms 2. Ovum secondary oocyte arrested at metaphase in the second meiotic division
Germ cell and fertilization Germ cell spermatozoon and ovum 1. Spermatozoon Capacitation：In female reproductive tract, the sperms were enabled to bind to the zona pellucida receptors. removal of glycoproteins (decapacitation factor) which cover the sperms 2. Ovum secondary oocyte arrested at metaphase in the second meiotic division
Fertilization: The process in which the spermatozoon penetrates into the ovum to form fertilized ovum In the ampulla of oviduct Ampulla site of fertilization (sperm cell penetrates oocyte) Uterine tube ocote rary Sperm cells deposited in vagina
Fertilization: The process in which the spermatozoon penetrates into the ovum to form fertilized ovum. In the ampulla of oviduct
Process of fertilization Sperm bind to sperm receptor ZP-3 induce Acrosome reaction: release of acrosomal enzyme Penetration and Cell release of acrosomal membrane nucleus acrosome enzyme of ovum sw
nucleus acrosome Penetration and release of acrosomal enzyme Cell membrane of ovum Process of fertilization Sperm bind to sperm receptor ZP-3 induce Acrosome reaction：release of acrosomal enzyme
ovum fertilized ovum sperm
ovum fertilized ovum sperm
c Zona reaction: Cortical granules-perivitelline space degrade zp-3, alteration of zona pellucida ->barrier for sperm penetration The second meiotic division of the secondary oocyte is rapidly lifted and the second ○ polar body is released leaving a haploid female nucleus
▪ The second meiotic division of the secondary oocyte is rapidly lifted and the second polar body is released, leaving a haploid female nucleus. Zona reaction: Cortical granules→perivitelline space →degrade ZP-3, alteration of zona pellucida →barrier for sperm penetration