8- e Renal output of water and salt Water and salt intake Equilibrium point 2 0 50 100 150 200 Arterial pressure(mm Hg) pressure-diuresis
pressure-diuresis
Output, urine output Intake. the water and salts from digestion tract and the water and salts flowing into vessels--blood volume Over a long period, the water and salt output must equal the intake The change in water is al ways parallel with the sa pressure-natriuresis or pressure-diuresis or renal function curve
Intake , the water and salts from digestion tract and the water and salts flowing into vessels—blood volume. Output, urine output Over a long period, the water and salt output must equal the intake. The change in water is always parallel with the salt. pressure-natriuresis or pressure-diuresis or renal function curve
e Renal output of water and salt Water and salt intake 6 EEx50b P↑→Uout↑ →BV↓→CO↓ P⊥stil Equilibrium point higher Q 0 50 100 150 200 P↓→Uout↓→BV ↑→CO↑→P↑ Arterial pressure(mm Hg) stl|ower→EQ
P↑ → Uout ↑ →BV ↓ →CO ↓ →P ↓still higher…. → EQ P ↓ → Uout ↓ →BV ↑ → CO ↑ →P ↑ still lower → EQ
Equilibrium point First, assume that the arterial pressure rises to 150 mm Hg, At this level, the graph shows that renal output of water and salt is about three times as great as the intake. Therefore, the body loses fluid, the blood volume decreases and the arterial pressure Furthermore this negative balance of fluid will not cease until the pressure falls all the way back exactly to the equilibrium evel. Indeed, even when the arterial pressure is only l mm hg greater than the equilibrium level, there still is more loss of water and salt than intake,So that the pressure continues to fall that last l mmHg until the pressure returns exactly to the equilibrium point Now, let us see what happens if the arterial pressure falls below the equilibrium point. This time the intake of water and salt is greater than the output. Therefore the body fluid volume increases the blood volume increases, and the arterial pressure rises until once again it returns exactly to the equilibrium point This return of the arterial pressure always exactly back to the equilibrium point is the infinite feedback gain principle for control of arterial pressure by the renal-body fluid mechanism
Equilibrium point First, assume that the arterial pressure rises to 150 mm Hg, At this level, the graph shows that renal output of water and salt is about three times as great as the intake. Therefore, the body loses fluid, the blood volume decreases, and the arterial pressure. Furthermore, this “negative balance” of fluid will not cease until the pressure falls all the way back exactly to the equilibrium level. Indeed, even when the arterial pressure is only 1 mm Hg greater than the equilibrium level, there still is more loss of water and salt than intake, so that the pressure continues to fall that last 1 mmHg until the pressure returns exactly to the equilibrium point. Now, let us see what happens if the arterial pressure falls below the equilibrium point. This time the intake of water and salt is greater than the output. Therefore, the body fluid volume increases, the blood volume increases, and the arterial pressure rises until once again it returns exactly to the equilibrium point. This return of the arterial pressure always exactly back to the equilibrium point is the infinite feedback gain principle for control of arterial pressure by the renal-body fluid mechanism
The pressure diuresis or natriuresis represents the relationship between arterial blood pressure. intake and urine output There will be very easy to understand following conclusions according to above principle
The pressure diuresis or natriuresis represents the relationship between arterial blood pressure, intake and urine output. There will be very easy to understand following conclusions according to above principle :