Primary afferent nociceptor A-beta fiber: largest-diameter fiber, respond maximally in nerves that innervate the skin. Normally, it does not produce pain °A- delta fiber:6-8μ m in diameter eC fiber: 2-4um in diameter unmyelinated Most a-delta and c afferents respond maximally only to intense(painful) stimuli and produce pain when they are electrically stimulated; this defines them as primary afferent nociceptors(pain receptors)
Primary afferent nociceptor •A-beta fiber: largest-diameter fiber, respond maximally in nerves that innervate the skin. Normally, it does not produce pain. •A-delta fiber: 6~8 m in diameter •C fiber: 2~4m in diameter, unmyelinated Most A-delta and C afferents respond maximally only to intense (painful) stimuli and produce pain when they are electrically stimulated; this defines them as primary afferent nociceptors (pain receptors)
Primary afferent Components of a typical cutaneous nerve Dorsal Root Ganglion Peripheral Nerve Spinal Cord AS C OD Sympathetic Sympathetic Preganglionic Postganglionic
Primary afferent Components of a typical cutaneous nerve