PD( phylogenetic diversity )whole tree otu es No orU ut on 20 Number of species Faith D P Conservation evaluation and phyloge rsity]. Biological Conservation, 1992, 61(1): 1
Faith D P. Conservation evaluation and phylogenetic diversity[J]. Biological Conservation, 1992, 61(1):1-10. http://www.berrygenomics.com/wp-content/uploads/2014/12/otu_tree.png
Effect of Anesthetic eye drops PD Whole Tree Observed species 53g5m25四9m Sequences Per Sample uences Per Sampl a diversity Sampling location Laboratory(n=116, conjunctiva Ophthalmology practice(n=75, conjunctiva Fig S1A
Fig.S1A α diversity
Effect of Anesthetic eye drops LDA Phylum-level Genus-level P:g_Pseu Fusobacteria* Cyanobacteria" f Enterobacteriaceae: g Bacteroidetes* P: g_ Neisseria Actinobacteria P: f Oxalobacteraceae Other* P: g_Sphingobium F:g_Anaerococcus :g Streptococcus Fig_Lactobacillus* F:g_Staphylo C; o_Streptophyta; f_:g A; g Rothia Laboratory Ophthalmologic Ophthalmologic g_coryneb Unassigned practice Laboratory practice Conjunctiva Conjunctiva Conjunctiva Conjunctiva n=116 n=75 n=116 Fig S1B
Fig.S1B LDA
Effect of Anesthetic eye drops Unweighted Weighted Pc2(4%) O Ophthalmologic practice Conjunctiva (N=75) O Ophthalmologic practice Conjunctiva(N=75) O Laboratory Conjunctiva(N=116) gl Ophthalmolog O Laboratory Conjunctiva( N=116) Laboratory a Aphtha malacic +-- aboratory 02040.60.8 p=0.001 Pc1(13% Pc1(54%) Fig S1C
Fig.S1C
Figure. PD Whole Tree Observed species Non-lens wearers Conjunctiva Lens wearers Non-lens wearers (n=63) Skin under the eve Lens wearers (n=51) Lens wea Contact lens 300 400 Phylogenetic diversity Number of observed species T-test
T-test