Proteins in Membrane bilayer Iypes Integral-Transmembrane >ionic channel, ionic pump, carrier, controller (G protein)
17 Proteins in Membrane Bilayer Types: ➢ Integral - Transmembrane: ➢ ionic channel, ionic pump, carrier, controller (G protein)
Integral proteins TRANSPORTERS LINKERS RECEPTORS ENZYMES EXTRACELLULAR SPACE CYTOSOL
18 Integral proteins
Proteins in Membrane bilayer Types: Peripheral -Lipid anchored and Protein anchored, located mainly at the inside of membrane surface enzymes, controllers
19 Proteins in Membrane Bilayer Types: ➢ Peripheral – Lipid anchored and Protein anchored, located mainly at the inside of membrane surface: ➢ enzymes, controllers
Peripheral proteins associated by weak electrostatic bonds to membrane proteins or lipids can be solubilized in high salt concentrations associations with membrane or protein may be dynamic: transient, and regulated 000000000 o∞oo6 DOgood 000 0. ser 王
20 Peripheral proteins ➢ associated by weak electrostatic bonds to membrane proteins or lipids, ➢ can be solubilized in high salt concentrations ➢ associations with membrane or protein may be dynamic: transient, and regulated arg p.ser. --- +++ +++ +++ +++--- --- ---
Membrane carbohydrates: Small amounts located at the extracellular surface in combination with membrane proteins or lipids glycoproteins or glycolipids Functions Negatively charged, let the cell to repel negative objects Attach cells one to another Acts as receptor substance for binding hormone such as Insulin Participate in immune reaction as antigen
21 Membrane Carbohydrates: ➢ Small amounts ➢ located at the extracellular surface. ➢ in combination with membrane proteins or lipids ➢ glycoproteins or glycolipids. ➢ Functions: ➢ Negatively charged, let the cell to repel negative objects ➢ Attach cells one to another ➢ Acts as receptor substance for binding hormone such as insulin ➢ Participate in immune reaction as antigen