HO-P phosphofructokinase CH2O-P 磷酸果糖激酶 M CH,OH ATP CH,- ADP 6-磷酸果糖 1,6二磷酸果糖 fructose-6-phosphate 1. 6-fructose-bisphosphate 反应不可逆
6-磷酸果糖 磷酸果糖激酶 ATP ADP Mg2+ 1，6二磷酸果糖 P CH2O-P CH2OH O CH2O-P CH2OO fructose-6-phosphate 1,6-fructose-bisphosphate phosphofructokinase 反应不可逆
2、1,6-二磷酸果糖 2分子磷酸丙糖 1, 6-fructose-bisphosphate triose phosphate CHO-P H,O-P C=0磷酸二羟丙酮 aldolase choh dihydroxyacetone 醛缩酶 phosphate triose phosphate isomerase CH,O-P CHO ,6二磷酸果糖 〔H2OH3-磷酸甘油醛 CHO-P glyceraldehydes-3-phosphate
2、1，6-二磷酸果糖 2分子磷酸丙糖 1,6-fructose-bisphosphate triose phosphate 1，6二磷酸果糖 CH2O-P C=O CH2OH CHO CH2OH CH2O-P 醛缩酶 磷酸二羟丙酮 3-磷酸甘油醛 P CH2O-P CH2OO aldolase glyceraldehydes-3-phosphate triose phosphate isomerase dihydroxyacetone phosphate
3、3-磷酸甘油醛 丙酮酸 glyceraldehydes-3-phosphate pyruvate glyceraldehydes-3-phosphate dehydrogenase CHO 3-磷酸甘油醛脱氢酶cooP CHOH CHOH H,O-P NAD+ NADH +H+ H,O-P 3-磷酸甘油醛 1,3二磷酸甘油酸 bisphosphoglycerate 糖酵解中唯一的一步脱氢
3、3-磷酸甘油醛 丙酮酸 glyceraldehydes–3-phosphate pyruvate CHO CH2OH CH2O-P COO CH2OH CH2O-P 3-磷酸甘油醛脱氢酶 ～P NAD+ NADH + H+ Pi 3-磷酸甘油醛 1,3二磷酸甘油酸 糖酵解中唯一的一步脱氢 bisphosphoglycerate glyceraldehydes-3-phosphate dehydrogenase
COoP 磷酸甘油酸激酶COOH CHOH CHOH CHO-P ADP ATP CH,O-P 1,3二磷酸甘油酸 3-磷酸甘油酸 bisphosphoglycerate 3-phosphoglycerate 底物水平磷酸化( substrate level phosphorylation) 生成ATP
COO CH2OH CH2O-P ～P 1,3二磷酸甘油酸 COOH CH2OH CH2O-P 磷酸甘油酸激酶 ADP ATP Mg2+ 3-磷酸甘油酸 底物水平磷酸化(substrate level phosphorylation) 生成ATP bisphosphoglycerate 3-phosphoglycerate
Phosphoglycerate mutase enolase 4O、变位酶COOH烯醇化酶OOH COoH CH CHO-P OCF CHO-P CH2OH H,0 CH2 3-磷酸甘油酸2-磷酸甘油酸磷酸烯醇式丙酮酸 3-phosphoglycerate phosphoenolpyruvate 2-phosphoglycerate
COOH CH2OH CH2O-P COOH CHO-P CH2OH COOH C-O～P CH2 = 变位酶 烯醇化酶 H2O 3-磷酸甘油酸 2-磷酸甘油酸 磷酸烯醇式丙酮酸 3-phosphoglycerate 2-phosphoglycerate Phosphoglycerate mutase enolase phosphoenolpyruvate