Medical Genetics 1 sickle celll anemia, hbs, AR Sickle cell anemia is a blood disorder that affects hemoglobin, a protein found in red blood cells that helps carry oxygen throughout the bod
Medical Genetics 1.1.2 sickle cell anemia, HbS，AR Sickle cell anemia is a blood disorder that affects hemoglobin, a protein found in red blood cells that helps carry oxygen throughout the body
Medical Genetics an abnormal form of hemoglobin Sickle cell anemia occurs whel (Hbs)is produced. Hbs molecules tend to clump together, making red blood cells sticky, stiff, and more fragile, and causing them to form into a curved, sickle shape
Medical Genetics Sickle cell anemia occurs when an abnormal form of hemoglobin (HbS) is produced. HbS molecules tend to clump together, making red blood cells sticky, stiff, and more fragile, and causing them to form into a curved, sickle shape
Medical Genetics The mutation causing sickle cell anemia is a single nucleotide substitution(a to t) in the codon for amino acid 6. The change is converts a glutamic acid codon (gag to a valine codon(GTG). The form of hemoglobin is persons with sickle cell anemia is referred to as hbs
Medical Genetics The mutation causing sickle cell anemia is a single nucleotide substitution (A to T) in the codon for amino acid 6. The change is converts a glutamic acid codon (GAG) to a valine codon (GTG). The form of hemoglobin is persons with sickle cell anemia is referred to as HbS
Medical Genetics Normal Sickle 6 Continuation of imino icids
Medical Genetics
Medical Genetics Hbs HbS Solution Fiber 6 Amino acid Triplet Codon Replacement OXy Deoxy A一一an一 Vaso-occlusion Cell Heterogeneity
Medical Genetics