Medical Genetics Hemoglobin 远
Medical Genetics Hemoglobin
Medical Genetics Heme F8 CD1 Helix A
Medical Genetics
Medical Genetics Protoporphotinin 1tl Coproporphyrinogen III Protophorphurtn-1x F之 Home succinuI-E0A A八yu samtnolevultnic ncnd DhDn。m C要重 Heme Biosynthesis The process begins in the mitochondrion with the condensation of succinyl-CoA and glycine to form 5 aminolevulinic acid. A series of steps in the cytoplasm produce coproporphrynogen Ill, which re-enters the mitochondrion. The final enzymatic steps produce heme
Medical Genetics Heme Biosynthesis. The process begins in the mitochondrion with the condensation of succinyl-CoA and glycine to form 5- aminolevulinic acid. A series of steps in the cytoplasm produce coproporphrynogen III, which re-enters the mitochondrion. The final enzymatic steps produce heme
Medical Genetics Beta globin gene cluster Chromosome 11 epsilon gannna delta beta Hb F Hb R2 Hb H alpha Globin Gene cluster Chromosome 16 Zeta 2 Zeta I Alpha AIpha 5 Schematic representation of the globin gene loci
Medical Genetics Schematic representation of the globin gene loci
Medical Genetics Embryonic Fetal hemoglobin hemoglobins Adult hemoglobins gower I zeta(2), epsilon(2) hemoglobin A gower 2 hemoglobin F alpha(2), beta(2) alpha(2), epsilon(2) alpha(2), gamma(2) hemoglobin A2 Portland pha(2), delta(2) zeta(2), gamma(2)
Medical Genetics Embryonic hemoglobins Fetal hemoglobin Adult hemoglobins gower 1: zeta(2), epsilon(2) gower 2: alpha(2), epsilon (2) Portland: zeta(2), gamma (2) hemoglobin F: alpha(2), gamma(2) hemoglobin A: alpha(2), beta(2) hemoglobin A2: alpha(2), delta(2)