MHCII分子相关的外源性抗原的提呈途径(Pathwayof MHCclassIIassociatedexogenous antigen presentation
MHC II分子相关的外源性抗原的提呈途径 （Pathway of MHC class II associated exogenous antigen presentation ）
Pathway of MHC class II associated细antigenpresentation香睡缓推摄取伪是善唯体安一容酶体客游体饰绿雨8exogenous antigen香唯滨精体1→>are taken up by APCsX吞噬细胞的吞噬杀伤过程示意图→processed intopeptides→ that bind to MHC II moleculesforming peptide/ MHC II complex→ transported to the cell surface→presented to CD4+Tcell
Pathway of MHC class II associated antigen presentation exogenous antigen → are taken up by APCs → processed into peptides → that bind to MHC II molecules forming peptide/ MHC II complex → transported to the cell surface → presented to CD4+T cell
Stages of exogenous antigen processingUPTAKEAccess of native antigens and pathogens tointracellular pathways of degradation
Stages of exogenous antigen processing 1. UPTAKE Access of native antigens and pathogens to intracellular pathways of degradation
VptakeofexogenousantigensMembraneIgreceptormediatedendocytosisPhagocytosisComplementreceptormediatedendocytosisinocytosisopsonizationFcreceptormediatedendocytosisVptake mechanisms direct antigen into intracellularvesiclesforexogenousantigenprocessing
Y Pinocytosis Phagocytosis Membrane Ig receptor mediated endocytosis Y Uptake of exogenous antigens Complement receptor mediated endocytosis Fc receptor mediated endocytosis opsonization Uptake mechanisms direct antigen into intracellular vesicles for exogenous antigen processing
2.DEGRADATIONProteolysis of antigens to peptides
2. DEGRADATION Proteolysis of antigens to peptides