Functional Anatomy of Stomach- Oesophagus naus Lower Oesophageal Sphincter Fundus Storage Body Storage Duodenum Mu UCUs Pylorus HCI oay Pepsinogen Antrum Intrinsic factor Antrum Mixing/Grinding Gastrin
11 Oesophagus Lower Oesophageal Sphincter Fundus Body Antrum Duodenum Pylorus Functional Anatomy of Stomach Fundus Body Antrum • Storage • Storage • Mucus • HCl • Pepsinogen • Intrinsic factor • Mixing/Grinding • Gastrin
Il 1 Gastric gland cells 1. Oxyntic gland(泌酸 Luren 腺) Gastric Mucus Parietal cell Chief cell Surface epithelial cells Mucous neck cell 2. Pyloric gland Mucous neck cells Mucus cell 3. Cardiac gland Oxyntic gastric) Mucus cell gland Oxyntic (parietaL cells 4. Endocrine cells(G,D ECL o/ Peptic (chief) cells ECL enterochromaffin-like cell
12 II.1 Gastric gland cells 1. Oxyntic gland (泌酸 腺） Parietal cell Chief cell Mucous neck cell 2. Pyloric gland Mucus cell 3. Cardiac gland Mucus cell 4. Endocrine cells (G, D, ECL) ECL:enterochromaffin-like cell
Exocrine gland cells of gastric pits Gastric lumen Produce aralia mucus that covers mucosa layer Gastric pit Mucous neck cells Synthesize and secrete the protease Chief cell precursor known as pepsinogen. Gland region g Parietal cells Synthesize and secrete the hcl acid responsible for the Muscularis mucosa acidic pH in the gastric lumen 13
13 Synthesize and secrete the HCl acid responsible for the acidic pH in the gastric lumen. Synthesize and secrete the protease precursor known as pepsinogen. Produce alkaline mucus that covers mucosa layer Exocrine gland cells of gastric pits
Structure of Stomach Wall Opening to gastric gland Epithelium mph esse amina Muscularis mucosae Arter Submucosa and vein Circula musc Submucosal plexus Longitudinal uscle steric Serosa lexus
14 Structure of Stomach Wall
IL 2 Composition and functio of gastric secretion 1. HCI converts pepsinogen to pepsin for chemical digestion provides optimal ph environment for pepsin destroys some bacteria stimulates the small intestinal mucosa to release secretinand CCK promotes the absorption of Ca and Fe in small intestine 15
15 II.2 Composition and function of gastric secretions 1. HCl ➢ converts pepsinogen to pepsin for chemical digestion ➢ provides optimal pH environment for pepsin ➢ destroys some bacteria ➢ stimulates the small intestinal mucosa to release secretinand CCK ➢ promotes the absorption of Ca and Fe in small intestine