10.Predict the major organic product of the following reaction. 1)NaOEt 2)H,0田 c am 。Y Cio Page6
Page 6 10. Predict the major organic product of the following reaction. O O + O O 1) NaOEt 2) H3O ? A) O O O B) O O O O C) O O D) O O O E) reaction does not occur Ans: D
11.What product results from treatment of the 1.2-diketone below with hydroxide? KOH,H2 100C Page7
Page 7 11. What product results from treatment of the 1,2-diketone below with hydroxide? A) O- Na+ OH O B) Na+ - O O OH C) HO O OH D) HO O E) OH OH Ans: A
12.What product would be expected to result from the reaction sequence shown? 3.NaOH.H2O,heat 4.H3O,heat CH2CH2CH2CH 8 H.CH2CO CH2CH2CH2CH3 HO OCH CH CH2CH2CH2CH HO E)HO2C-CH2CH2CH2CH2CH3 Ans:E Page8
Page 8 12. What product would be expected to result from the reaction sequence shown? H3CH2CO OCH2CH3 O O 1. NaOCH2CH3 2. CH3CH2CH2CH2Br 3. NaOH, H2O, heat 4. H3O+ , heat ? A) H3CH2CO CH2CH2CH2CH3 O O B) H3CH2CO OCH2CH3 O O CH2CH2CH2CH3 C) HO OCH2CH3 O O CH2CH2CH2CH3 D) HO OH O O CH2CH2CH2CH3 E) HO2C-CH2CH2CH2CH2CH3 Ans: E
13.Which of the following reaction sequences will affect the following transformation c20 1)n-BuLi/THF 。 3)H,0 B) 1)n-BuLi/THF 心r 。 4)H0 9 1)NaH/THF 3)H,0 D) Page9
Page 9 13. Which of the following reaction sequences will affect the following transformation? H O ? O OH A) 1) n-BuLi / THF 3) H3O+ O H 2) B) 1) n-BuLi / THF 4) H3O+ O H 3) 2) N , H+ C) 1) NaH / THF 3) H3O+ 2) O D)