Leukoplakia idiopathic leukoplakia tobacco-associated leukoplakia Leukoplakic-like lesion associated with the known cause frictional keratosis Department of Oral Pathology, Shandong University 6
Department of Oral Pathology, Shandong University 6 Leukoplakia idiopathic leukoplakia tobacco-associated leukoplakia Leukoplakic-like lesion associated with the known cause frictional keratosis
cadence 10.47%(include smokers keratosis and frictional keratosis)(1980) Pre-cancerous lesion 3%-5%malignant transformation Department of Oral Pathology, Shandong University
Department of Oral Pathology, Shandong University 7 Incedence: 10.47% (include smoker’s keratosis and frictional keratosis) (1980). Pre-cancerous lesion 3%—5% malignant transformation
【 Etiology】 Etiology likely to be multifactorial Tobacco smoking or snuff dipping aLcohol Betel quid usage o Mutation of the p53 gene iDiopathic Department of Oral Pathology, Shandong University 8
Department of Oral Pathology, Shandong University 8 【Etiology 】 Etiology likely to be multifactorial Tobacco smoking or snuff dipping Alcohol Betel quid usage Mutation of the p53 gene Idiophathic
Clinical features) 白斑可发生在口腔各部位粘膜,以 颊、舌粘膜最为多见。男性较为多发 男女之比为13.5:1。白斑为灰白色或乳 白色斑块,边界清楚,与粘膜平齐或略 为高起,舌舔时有粗涩感。 Department of Oral Pathology, Shandong University 9
Department of Oral Pathology, Shandong University 9 【Clinical features】 白斑可发生在口腔各部位粘膜，以 颊、舌粘膜最为多见。男性较为多发， 男女之比为13.5 : 1。白斑为灰白色或乳 白色斑块，边界清楚，与粘膜平齐或略 为高起，舌舔时有粗涩感
Clinical features) 根据临床表现可分为 均质型 Homogeneous 非均质型 Non-homogeneous Department of Oral Pathology, Shandong University 10
Department of Oral Pathology, Shandong University 10 【Clinical features】 根据临床表现可分为 均 质 型 Homogeneous 非均质型 Non-homogeneous