Cholesterol polar head groups cholesterol- stiffened region more fluid region Cholesterol in the membrane decreases the permeability of the bilayer to small water-soluble molecules and at high concentration inhibits possible phase transition to crystallizing
Some functions of phospholipids in cell signaling (A) extracellular extracellular sigt signal activated phosphorylated signaling receptor inositol protein phospholipids c receptor protein fragments H2C-CH-CH? CYTOSOL docked intracellular aling elay signal PI 3-ki m prc otein phospholipase C elay signal Phospholipase lavage site