k Resistance to breathing Elastic of the lung Elastic compliance I/RL=△VL△Pu(L/cmH2O) Static compliance(Cst) of the lung S shaped curve, divided into 3 portions Flattened upper portion Steep middle portion Flattened lower portion Special compliance( C= CU/TLC
* Resistance to breathing Elastic ~ of the lung Elastic ~ & Compliance CL=1/RL=VL/PL(L/cmH2O) Static compliance (Cst) of the lung S shaped curve, divided into 3 portions Flattened upper portion Steep middle portion Flattened lower portion Special compliance (Csp) Csp = CL/TLC
0.5 肺容积~L 呼气 0.25 吸气 Static compliance(Cst) of the lung
Static compliance (Cst) of the lung
100 △v 40 △F FRI RV 20 0 S shaped compliance curve of the lung
S shaped compliance curve of the lung
Source of elastic of the lung Elastic tissue(1/3)& Alveolar surface tension(2/3) Pulmonary surfactant Nature: A lipoprotein, Main lip component is DPL Characteristics: Both hydro-philia &-phobicity Source: Type I alveolar epithelial cells Distribution Inner surface of the alveoli Action: Reduce the alveolar surface tension Significance: Decrease the inspiratory resistance, Stabilize the volume &e pressure in the alveoli, Prevent pulmonary edema
Source of elastic ~ of the lung Elastic tissue (1/3) & Alveolar surface tension (2/3) Pulmonary surfactant Nature: A lipoprotein, Main lip component is DPL Characteristics: Both hydro-philia & -phobicity Source: Type II alveolar epithelial cells Distribution: Inner surface of the alveoli Action: Reduce the alveolar surface tension Significance: Decrease the inspiratory resistance, Stabilize the volume & pressure in the alveoli, Prevent pulmonary edema
200 流生理盐水 萎陷 150 充气 肺容积~m 100 Pulmonary 50 compliance curve when 0 16 2 filled with air 肺内压(cmH20) or saline
Pulmonary compliance curve when filled with air or saline