Serum aminotransferases have been used as clinical markers of tissue damages Damaged heart or liver cells leak aminotransferases Blood aspartate aminotransferase and alanine aminotransferase are usuall examined for indications of illness
Serum aminotransferases have been used as clinical markers of tissue damages • Damaged heart or liver cells leak aminotransferases. • Blood aspartate aminotransferase and alanine aminotransferase are usually examined for indications of illness
氨基酸碳架的分解 1.进入TCA循环 丙氨酸 精氨酸 苏氨酸 组氯酸 甘氨酸 谷氨髋胺 丝氨酸 脯氨酸 半胱氨酸 异柠檬酸、 谷氨酸 丙酮酸 也产生乙酰CoA 柠檬酸 a-酮戊二酸 乙酰CoA 异亮氨酸 琥珀酰CoA 甲硫氨酸 缬氨酸1 乙酰乙酰CoA 虢珀酸 草酰乙酸 苯因氨酸 苯丙氨酸 延胡索酸 酪氨酸 酪氨酸 亮氨酸 苹果酸 赖氨酸 色氨酸 天冬氨酸 天冬酰胺
三. 氨基酸碳架的分解 氨基酸脱羧酶 1. 进入TCA循环
Leucine Arginine Lysine Glutamine Phenylalanine Histidine Tryptophan Glutamate Proline Tyrosine Isocitrate a-Ketoglutarate Isoleucine Methionine Threonine Acetoacetyl-CoA Valine Citric Citrate acid Succinyl-CoA cvcle Acetyl-CoA Succinate Oxaloacetate Fumarate Phenylalanine Tyrosine Malate Pyruvate Oxidation of the Alanine Cysteine carbon skeletons of Isoleucine Leucine Serine Asparagine amino acids in Tryptophan Tryptophan Aspartate mammals
Oxidation of the carbon skeletons of amino acids in mammals