20· Chapter1:ChemDraw Basics CambridgeSof Closing ChemDraw
20 • Chapter 1: ChemDraw Basics CambridgeSoft Closing ChemDraw Administrator
Chapter 2:Tutorials Overview 3.Type tut1.cdx in the appropriate text box. 4.Select a folder in which to save the file. The tutorials are designed to teach you the fundamental drawing techniques available in 5.Click Save. ChemDraw.Before you begin,you may want to 6.From the View menu,choose Show General review“Conventions'”on page2 to familiarize Toolbar. yourself with the terminology used in the tutorials. 7.From the View menu,choose Show Info You may also want to use your Quick Reference Window. Card while you perform the tutorials. The Info window appears and displays drawing ChemDraw automatically checks for correct parameters as you draw. chemical syntax as you draw.If ChemDraw finds a potential problem,a red box is displayed around the erroneous object.The red box is displayed on screen only and does not print. To disable the automatic error checking onaspecific object: Right-click the object and deselect Display 3 Warnings. Tutorial 1:Reaction Schemes 8.Click the Object menu and make sure there is a In this tutorial,you will draw the following check mark next to the Fixed Lengths and (simplified)reaction scheme Fixed Angles commands.Ifeither command is not checked.choose it. NOTE:Applying fixed lengths and fixed angles enables you to create structures with consistent OH bond lengths and angles.The fixed length dimension 4-hydroxy-4-methy2-pentanon is set in the Dr awing Settings dialog box.The fixed angle dimension increments angles by 15 degrees. Create a ChemDraw Document 1.Start ChemDraw. 2.From the File menu,choose Save As. ChemDraw 7 Chapter 2:Tutorials 21 Tutorial 1:Reaction Schemes
ChemDraw 7 Chapter 2: Tutorials • 21 Tutorial 1: Reaction Schemes Chapter 2: Tutorials Overview The tutorials are designed to teach you the fundamental drawing techniques available in ChemDraw. Before you begin, you may want to review “Conventions” on page 2 to familiarize yourself with the terminology used in the tutorials. You may also want to use your Quick Reference Card while you perform the tutorials. ChemDraw automatically checks for correct chemical syntax as you draw. If ChemDraw finds a potential problem, a red box is displayed around the erroneous object. The red box is displayed on screen only and does not print. To disable the automatic error checking on a specific object: • Right-click the object and deselect Display Warnings. Tutorial 1: Reaction Schemes In this tutorial, you will draw the following (simplified) reaction scheme: Create a ChemDraw Document: 1. Start ChemDraw. 2. From the File menu, choose Save As. 3. Type tut1.cdx in the appropriate text box. 4. Select a folder in which to save the file. 5. Click Save. 6. From the View menu, choose Show General Toolbar. 7. From the View menu, choose Show Info Window. The Info window appears and displays drawing parameters as you draw. 8. Click the Object menu and make sure there is a check mark next to the Fixed Lengths and Fixed Angles commands. If either command is not checked, choose it. NOTE: Applying fixed lengths and fixed angles enables you to create structures with consistent bond lengths and angles. The fixed length dimension is set in the Drawing Settings dialog box. The fixed angle dimension increments angles by 15 degrees. O OH O OH 4-hydroxy-4-methyl-2-pentanone 1 mole 2-propanone 2 moles
Create a bond Change a single bond into a double bond 1.Click the Solid Bond tool 1.Point to the atom shown below and hold the 2.Position the pointer(+)anywhere in the mouse button down. document window and click. The bond is extended to its fixed length at a 30-degree angle. X 2.Drag as shown below over the existing single bond.Release the mouse button Add a second bond: 1.Point to the right atom of the bond. 出 ! 2.Click the atom to add a bond. Add labels to the structure: A second bond is drawn,forming a 120-degree 1.Point to the atom shown below. angle between the bonds. 出 NOTE:The angle used when clicking to add bonds is controlled by the Chain Angle setting 2.Double-click the atom in the Drawing Settings dialog box in the File menu.If this bond angle cannot be established. the next smaller and logical bond angle is used. Add a third bond 1.Continue pointing to the atom shown below 3.Type an uppercase in the text box that appears. 2.Click the atom to add a bond 22 Chapter 2:Tutorials Tutorial 1:Reaction Schemes
22 • Chapter 2: Tutorials CambridgeSoft Tutorial 1: Reaction Schemes Administrator Create a bond: 1. Click the Solid Bond tool . 2. Position the pointer (+) anywhere in the document window and click. The bond is extended to its fixed length at a 30-degree angle. Add a second bond: 1. Point to the right atom of the bond. 2. Click the atom to add a bond. A second bond is drawn, forming a 120-degree angle between the bonds. NOTE: The angle used when clicking to add bonds is controlled by the Chain Angle setting in the Drawing Settings dialog box in the File menu. If this bond angle cannot be established, the next smaller and logical bond angle is used. Add a third bond: 1. Continue pointing to the atom shown below. . 2. Click the atom to add a bond. Change a single bond into a double bond: 1. Point to the atom shown below and hold the mouse button down. 2. Drag as shown below over the existing single bond. Release the mouse button. Add labels to the structure: 1. Point to the atom shown below. 2. Double-click the atom. 3. Type an uppercase O in the text box that appears.
4.Close the text box by doing one of the following: NOTE:When yo cop s show above you can drag it anywhere in the document window Click in an empty area of the window If you want the copy to remain aligned with the ·Click another tool. original,hold Shift while dragging. Next,you duplicate a structure and then create another structure from the duplicate. Modify the duplicated structure: Duplicate the structure 1.Click the Solid Bond tool 1.Click the Lasso tool 2.Point.in the copied structure.to the atom shown below and click The last structure drawn is automatically selected. 2.Point over the Selection Rectangle Add several bonds to a single atom: . 1.Point to the atom shown below 3.Press and hold Ctrl(Windows)or Option (Macintosh). The hand pointer with a plus sign indicates tha you are in the duplication mode of a selection 必 tool. 2.Click the atom three times,allowing a pause between each click. NOTE:If you click too fast.the click is interpreted eitherasa double click,which Drag the Selection Rectangle to the right opens a text box or a triple-click.which duplicates your last atom label. A copy of the structure appears as you begin drag.The original structure remains in its position.Release the mouse button when the copy is clear of the origina ChemDraw 7 Chapter 2:Tutorials 23 Tutorial 1:Reaction Schemes
ChemDraw 7 Chapter 2: Tutorials • 23 Tutorial 1: Reaction Schemes 4. Close the text box by doing one of the following: • Click in an empty area of the window. • Click another tool. Next, you duplicate a structure and then create another structure from the duplicate. Duplicate the structure: 1. Click the Lasso tool . The last structure drawn is automatically selected. 2. Point over the Selection Rectangle. 3. Press and hold Ctrl (Windows) or Option (Macintosh). The hand pointer with a plus sign indicates that you are in the duplication mode of a selection tool. 4. Drag the Selection Rectangle to the right. A copy of the structure appears as you begin drag. The original structure remains in its position. Release the mouse button when the copy is clear of the original. NOTE: When you create a copy as shown above you can drag it anywhere in the document window. If you want the copy to remain aligned with the original, hold Shift while dragging. Modify the duplicated structure: 1. Click the Solid Bond tool . 2. Point, in the copied structure, to the atom shown below and click. Add several bonds to a single atom: 1. Point to the atom shown below. 2. Click the atom three times, allowing a pause between each click. NOTE: If you click too fast, the click is interpreted either as a double-click, which opens a text box or a triple-click, which duplicates your last atom label. O O O
Create an atom label using HotKeys.HotKeys are In the following steps,you use a different method keys on your keyboard that are linked to specific for selecting structures and then separate the atom labels for more information about hotkevs structures to make room for an arrow. see"Labeling Atoms with HotKeys"on page 73 1.Click the Marquee tool 1.Point to the atom shown below NOTE:Alternatively.you can select the Lasso tool and hold Al to use the Marquee tool. The last object drawn is selected. Drag the selection to make room for an arrow: 2.Type O or o. Press Shift to maintain the alignment of the structure and drag the Selection Rectangle to the right. OH When you use HotKeys that represent a single element,the correct number of hydrogen atoms is Add arrows to the reaction scheme added to the label. Align the structures: 1.Click the Arrow tootodisplay the Arrow palette. 1.Select the structures 2.On the Object menu,point to Align,and ther NOTE:The triangle in the lower right corne choose T/B centers. of the Arrow icon indicates it contains a palette You structures should appear as shown below. 2.Click and hold the palette title bar and drag the palette to the location you want. 24 Chapter 2:Tutorials CambridgeSof Tutorial 1:Reaction Schemes
24 • Chapter 2: Tutorials CambridgeSoft Tutorial 1: Reaction Schemes Administrator Create an atom label using HotKeys. HotKeys are keys on your keyboard that are linked to specific atom labels. For more information about HotKeys, see “Labeling Atoms with HotKeys” on page 73. 1. Point to the atom shown below. 2. Type O or o. When you use HotKeys that represent a single element, the correct number of hydrogen atoms is added to the label. Align the structures: 1. Select the structures. 2. On the Object menu, point to Align, and then choose T/B centers. You structures should appear as shown below. In the following steps, you use a different method for selecting structures and then separate the structures to make room for an arrow. 1. Click the Marquee tool . NOTE: Alternatively, you can select the Lasso tool and hold Alt to use the Marquee tool. The last object drawn is selected. Drag the selection to make room for an arrow: • Press Shift to maintain the alignment of the structure and drag the Selection Rectangle to the right. Add arrows to the reaction scheme. 1. Click the Arrow tool to display the Arrow palette. NOTE: The triangle in the lower right corner of the Arrow icon indicates it contains a palette. 2. Click and hold the palette title bar and drag the palette to the location you want. O O OH O O OH