Heterogeneous APs in heart Action Potentials SA Node Atrial Muscle A-V Node His Bundle HB Branches Purkinje Fibers Ventricular Muscle 0 M.D QRS 0.2 0.4s 0.6
Heterogeneous APs in heart
INa/Ca ICa(L) If Ik Ica(T) 窦房结细胞动作电位时程中的参与电流 Currents underlying depolarization in SA nodal cells)
窦房结细胞动作电位时程中的参与电流 （Currents underlying depolarization in SA nodal cells ）
Cardiac arrhythmias Tachy-cardiac arrhythmias -Atrial-premature beats -Atrial flutter -Atrial fibrillation (AF) -Ventricular-premature beats (contractions) -Ventricular-tachycardia (VT) -Ventricular fibrillation (VF) Brady-cardiac arrhythmias -Bundle branch blocks -Sinus bradycardia(Sick Sinus Syndrome)
Cardiac arrhythmias Tachy-cardiac arrhythmias -Atrial-premature beats -Atrial flutter -Atrial fibrillation (AF) -Ventricular-premature beats (contractions) -Ventricular-tachycardia (VT) -Ventricular fibrillation (VF) Brady-cardiac arrhythmias -Bundle branch blocks -Sinus bradycardia (Sick Sinus Syndrome)
Mechanisms of Arrhythmias Disturbance of impulse formation oDisturbance of impulse conduction ●both
Mechanisms of Arrhythmias Disturbance of impulse formation Disturbance of impulse conduction both
Mechanisms of Arrhythmias 1.心肌自律性增高 (increase in pacemaker rate) 4相自动除极速率加快 阈电位下移 最大舒张电位上升 INa/Ca 1Ca(L) It. Ik Ica(T)
Mechanisms of Arrhythmias 1. 心肌自律性增高 (increase in pacemaker rate) 4相自动除极速率加快 阈电位下移 最大舒张电位上升