口腔医学和外科 Anesthesia(麻醉) · born in1819 In 1840 enrolled at the world 's first dental school Baltimore College of Dental Surgery. Quit for money In 1844 became a student at harvard medical School charles Jackson, who demonstrated the magic of ether (Z ivk)in 1844), quit again for money In 1846, conducted first painless extraction in his office In 1846, first ether anesthesia operation for public(Dr Warren removed a vascular tumor) Life-time litigation for patent 可以重复验证的手术方案
口腔医学和外科 Anesthesia （麻醉） • born in 1819 • In 1840 enrolled at the world's first dental school, Baltimore College of Dental Surgery. Quit for money… • In 1844 became a student at Harvard Medical School. (Charles Jackson, who demonstrated the magic of ether （乙醚） in 1844), quit again for money… • In 1846, conducted first painless extraction in his office. • In 1846, first ether anesthesia operation for public (Dr Warren removed a vascular tumor) • Life-time litigation for patent… • 可以重复验证的手术方案
口腔医学和内和 Osteonecrosis of」aW (ONJ) ONJ may caused by systemic medications radiation infection direct chemical toxicity trauma and other etiologies th Africa. All rights reserve Whitt and Dr. Corey J. Auch, University of Missouri-Kansas City
口腔医学和内科 Osteonecrosis of Jaw （ＯＮＪ） • ONJ may caused by systemic medications,, radiation, infection, direct chemical toxicity, trauma, and other etiologies
口腔医学和内科 Fosamax Medical concern: osteoporosis in postmenopausal women Medical solution: synthetic drug analogue of pyrophosphate, such as Fosamax, acts primarily on bone to inhibit its re-sorption and was introduced in 1995 Top 20th; >20 mp/year; >3 b/year;
口腔医学和内科 Fosamax Medical concern: osteoporosis in postmenopausal women. Medical solution: synthetic drug analogue of pyrophosphate, such as Fosamax, acts primarily on bone to inhibit its re-sorption and was introduced in 1995. Top 20th； >20 mp/year; >3 b/year；
口腔医学和内科 (ONJ& Fosamax) Dental Operation-related ONJ(.1-0.4%) Patients taking Fosamax: ONJ (4%) Dental observation Fosamax may cause ONJ ·组织再生是 OSTEOBLAST和 OSTEOCLAST的平 衡
口腔医学和内科 （ＯＮＪ & Fosamax） • Dental Operation-related ONJ (0.1-0.4%） • Patients taking Fosamax: ONJ (4%) • Dental observation: Fosamax may cause ONJ • 组织再生是OSTEOBLAST和OSTEOCLAST的平 衡
口腔医学与生命科学 Discovery of Growth Factors During World War ll, Dr. Rita Levi-Montalcini conducted experiments from a home laboratory studying the growth of nerve fibers in chicken embryos 1950, Dr. Rita Levi-Montalcini initiated a study on ngr 953, Dr Stanley cohen joined the group and start to work on purification of NGF Snake saliva was used as a nuclease, and it led to the discovery of nGf in saliva Saliva gland promoted tooth eruption and eye openings led to the discovery of egf in 1962 Both received nobel prize in 1986 ·口腔组织是极有特色的实验材料
口腔医学与生命科学 Discovery of Growth Factors • During World War II, Dr. Rita Levi-Montalcini conducted experiments from a home laboratory, studying the growth of nerve fibers in chicken embryos. • 1950, Dr. Rita Levi-Montalcini initiated a study on NGF. • 1953, Dr. Stanley Cohen joined the group and start to work on purification of NGF. • Snake saliva was used as a nuclease, and it led to the discovery of NGF in saliva. • Saliva gland promoted tooth eruption and eye openings led to the discovery of EGF in 1962. • Both Received Nobel Prize in 1986 • 口腔组织是极有特色的实验材料