、化学历程 HMP途径 葡萄糖氧化脱羧 The gluconolactone(葡糖酸内酯) produced in step1 is hydrolytically unstable and readily undergoes a spontaneous ring-opening hydrolysis, although an enzyme, gluconolactonase, accelerates thIs reaction
The gluconolactone (葡糖酸内酯) produced in step 1 is hydrolytically unstable and readily undergoes a spontaneous ring-opening hydrolysis, although an enzyme, gluconolactonase, accelerates this reaction. 葡萄糖氧化脱羧 二、化学历程 HMP途径
、化学历程 HMP途径 葡萄糖氧化脱羧第二步: hydrolysis Step 2 COO 2-0.POCH HCOH Gluconolactonase HOCH OH O HO HCOH OH HO H HCOH 6-P-D-Gluconolactone CHoOPO 6-P-D-Gluconate 此反应不可逆,从而使G-6-P→6-磷酸葡萄糖酸 (6- phospho-D-gluconate)的过程不可逆
葡萄糖氧化脱羧 第二步：hydrolysis 二、化学历程 HMP途径 此反应不可逆，从而使 G-6-P → 6-磷酸葡萄糖酸 （6-phospho-D-gluconate）的过程不可逆