Regulation of Testis Function Hypothalamic-Pituitary-Testis Axis (1)GnRH GnRH KEY Hypothalamus Integrating center (2)LH Efferent path Effector testosterone Anterior Tissue response pituitary FSH LH (3)FSH Leydig cells Inhibin Spermatocyte Testosterone (T) inhibin Testes Second Sertoli cell messenger To body for secondary Cell effects Sertoli products cell Androgen-binding protein(ABP)
Regulation of Testis Function Hypothalamic-Pituitary-Testis Axis (1)GnRH (2)LH testosterone (3)FSH inhibin
下丘脑 GnRH 下丘脑 GnRH ◆抑制 睾酮抑制GnR阳的合成 兴奋 腺垂体 睾酮 LH 腺垂体 H FSH 睾酮促进第二 循环系统 性征出现和 精子的生成 LH刺激间质细胞 间质细胞 曲细精管 产生皋酮 睾酮 皋酮 粤丸 性器官和 男性的性发育 第二性征 精子生成