Anhui Medical University *mesonephros consists of glomeruli and mesonephric tubules which open laterally into mesonephric duct,a continuation of the pronephric duct .mesonephric duct opens into cloaca .Most of the mesonephros Mesonephric tubule degenerates Mesonephri duct .But tubules and ducts have derivatives in adult male reproductive structures
Anhui Medical University •Most of the mesonephros degenerates •But tubules and ducts have derivatives in adult male reproductive structures •mesonephros consists of glomeruli and mesonephric tubules which open laterally into mesonephric duct, a continuation of the pronephric duct •mesonephric duct opens into cloaca Mesonephric duct Mesonephric tubule
Anhui Medical University 3.Metanephros Segmented intermediate mesoderm (pronephric system) Vestigial pronephric system permanent kidneys begin development early fifth week u● Unsegmented ☆ intermediate mesoderm Allantoi Meso (mesonephric system) nephric *develop from the excretory Cloaca units ureteric bud and Unsegmented mesoderm Ureteric bud A (metanephric system) B the metanephrogenic tissue .Function begins at 11th-12th week urine produced and released into amniotic fluid
Anhui Medical University •permanent kidneys •begin development early fifth week •develop from the ureteric bud and the metanephrogenic tissue •Function begins at 11th-12th week •urine produced and released into amniotic fluid 3. Metanephros
Anhui Medical University (1)ureteric bud The ureteric bud is formed from an outgrowth of the mesonephric duct near the cloaca Developing into the ureter,renal pelvis,major and Mesonephric duct minor calyces Remnant of pronephros B and collecting tubules Ureteric bud Mesonephros Renal pelvis -Developing liver Major calix Nephrogenic cord Minor calix Renal pelvis Mesonephric duct Cloaca- Mesenchymal cell cluster Metanephric mass of mesoderm nter E Groove between lobes A Arched colecting tubul The rH Compan ne
Anhui Medical University (1)ureteric bud The ureteric bud is formed from an outgrowth of the mesonephric duct near the cloaca Developing into the ureter, renal pelvis, major and minor calyces and collecting tubules
Anhui Medical University >Human E35-37,epithelia bud at end of mesonephric duct -ureteric bud Metanephrogenic >ureteric bud induced by blastema metanephric mesenchyme to ureteric differentiate into collecting tubules, bud calyces,renal pelvis,ureter minor calyces ureteric bud associated with Major calyces metanephric mesenchyme nephron
Anhui Medical University Human E35-37, epithelia bud at end of mesonephric duct -ureteric bud ureteric bud induced by metanephric mesenchyme to differentiate into collecting tubules, calyces, renal pelvis, ureter Metanephrogenic blastema ureteric bud minor calyces Major calyces ureteric bud associated with metanephric mesenchyme nephron
Anhui Medical University (2)Metanephrogenic tissue The metanephrogenic tissue formed from the caudal portion of the intermediate mass of mesonephric ridge,and surrounds the end of the ureteric bud. Segmented intermediate mesoderm (pronephric system) Vestigial pronephric system duc Unsegmented intermediate Allantois mesoderm Meso esonephric system nephric excreto Cloaca units Mesonephric Mesonephric duct duct Unsegmented mesoderm Ureteric bud (metanephric system) B
Anhui Medical University The metanephrogenic tissue formed from the caudal portion of the intermediate mass of mesonephric ridge , and surrounds the end of the ureteric bud. (2)Metanephrogenic tissue