Infective endocarditis Infective endocarditis(IE)is characterized by colonization or invasion of the heart valves or the mural endocardium by a microbiologic agent, leading to the formation of bulky, friable vegetations laden with organisms. ■
Infective endocarditis ◼ Infective endocarditis(IE) is characterized by colonization or invasion of the heart valves or the mural endocardium by a microbiologic agent, leading to the formation of bulky, friable vegetations laden with organisms
Traditional ie has been classified on clinical grounds into acute and subacute forms Both rheumatic heart disease and infective endocarditis are common topics in examinations
◼ Traditional IE has been classified on clinical grounds into acute and subacute forms. Both rheumatic heart disease and infective endocarditis are common topics in examinations
An acute infective endocarditis on the mitral valve has spread into the septum all the way to the tricuspid valve, producing a fistula
An acute infective endocarditis on the mitral valve has spread into the septum all the way to the tricuspid valve, producing a fistula
An subacute infective endocarditis. The aortic valve demonstrates a large, irregular reddish tan vegetation
An subacute infective endocarditis. The aortic valve demonstrates a large, irregular, reddish tan vegetation
Microscopically, the valve in infective endocarditis demonstrates friable vegetations of fibrin and platelets (pink) mixed with inflammatory cells and bacterial colonies(blue). The friability explains how portions of the vegetation can break off and embolize
Microscopically, the valve in infective endocarditis demonstrates friable vegetations of fibrin and platelets (pink) mixed with inflammatory cells and bacterial colonies (blue). The friability explains how portions of the vegetation can break off and embolize