Immediate and Late-Phase Reactions Wheal-and-flare reaction Late-phase reaction (lasts up to 30 min post (develops approximately injection) eight hours later and persists several hours)
Immediate and Late-Phase Reactions Wheal-and-flare reaction (lasts up to 30 min post injection) Late-phase reaction (develops approximately eight hours later and persists several hours)
IgE response is a local event site of allergen entry local synthesis results in sensitization of local mast cells spillover of IgE enters circulation and sensitizes mast cells and basophils systemically
IgE response is a local event ◼ site of allergen entry ◼ local synthesis results in sensitization of local mast cells ◼ spillover of IgE enters circulation and sensitizes mast cells and basophils systemically