Basic pathologic change 1. Hypercelullarity 2. Thickening of GBM 3. Inflammatary exudation and necrosis 4. Hyaline change and sclerosis
Basic pathologic change 1. Hypercelullarity 2. Thickening of GBM 3. Inflammatary exudation and necrosis 4. Hyaline change and sclerosis
Areas° lesions Diffuse: affecting all or a majority of glomeruli Focal; affecting a few or a part of glomeruli Globic: involving the whole glomerulus Segmental: involving only segments of each glomerulus
Areas of lesions Diffuse: affecting all or a majority of glomeruli Focal: affecting a few or a part of glomeruli Globic: involving the whole glomerulus Segmental: involving only segments of each glomerulus
弥漫性病变球性病变 局灶性病变节段性病变 s'iarred glomar us
弥漫性病变球性病变 局灶性病变节段性病变
Clinical manifestations Acute nephritic syndrome o The nephrotic syndrome o Asymptomatic hematuria or proteinuria o Rapidly progressive nephritic syndrome o Chronic nephritic syndrome
Clinical manifestations ⚫ Acute nephritic syndrome ⚫ The nephrotic syndrome ⚫ Asymptomatic hemauria or proteinuria ⚫ Rapidly progressive nephritic syndrome ⚫ Chronic nephritic syndrome
Pathologic Types 1. Acute diffuse proliferative GN 2. Rapidly progressive GN 3. Membranous gn Membranoproliferative GN
Pathologic Types 1. Acute diffuse proliferative GN 2. Rapidly progressive GN 3. Membranous GN 4. Membranoproliferative GN