b, stratum spinosum structure LM,=4-10 layers polygonal cell with large round nucleus spinous processes slight basophilic cytoplasm EM: -tonofibrils lamellated granules /100-300nm membrane-coated /contain phospholipid and steroid intercellular bridges- Desmosome
b. stratum spinosum ---structure: LM: -4-10 layers polygonal cell with large round nucleus -spinous processes -slight basophilic cytoplasm EM: -tonofibrils -lamellated granules: /100-300nm membrane-coated /contain phospholipid and steroid -intercellular bridges- Desmosome
C Stratum granulosum -structure LM:-3-5 layers flattened cell - muclei begin to degenerate-stained slightly keratohyalin granules: basophilic EM: -keratohyalin granules: With tonofilament insert into them -lamellated granules: fused with cell membrane keratohyalin tonofilament keratin
c. stratum granulosum ---structure: LM: -3-5 layers flattened cell -muclei begin to degenerate-stained slightly -keratohyalin granules: basophilic EM: -keratohyalin granules: with tonofilament insert into them -lamellated granules: fused with cell membrane * keratohyalin + tonofilament = keratin