Morphology & Identification Gram positive Facultative anaerobes Grape like-clusters Catalase positive Major components of normal flora

Manifestations of Infection: Signs and symptoms vary according to the site and severity of infection. Diagnosis requires a composite of information, including history, physical examination, radiographic findings, and laboratory data. Microbial Causes of Infection: Infections may be caused by bacteria, viruses, fungi, and parasites. The pathogen may be exogenous (acquired from environmental or animal sources or from other persons) or endogenous (from the normal flora)

Symbioses Commensalism: one partner benefits and the other is neither harmed nor benefited. Mutualism: both partners benefit. Parasitism: one partner benefits at the expense of the other

Bacterial genomics Organisation Linear chromosomes Borrelia burgdorferi Streptomyces coelicolor Multiple chromosomes Vibrio cholerae Plasmids Borrelia burgdorferi

Bacteriophages ( phages ) are obligate intracellular parasites that multiply inside bacteria by making use of some or all of the host biosynthetic machinery . They are viruses that infect bacteria

The process of destroying all microbial forms. A sterile object is one free of all microbial forms, including bacterial spores

Bacterial chemical components Water: free water and compound water. Inorganic salt: phosphus, potassium magnesium,calcium, nitrium,etc. Protein: 50%-80% of dry weight accordingbacterial kinds and age. Sugar: mainly distributing in cell wall andcapsule. Lipids: composed of lipid, fatty acid, wax, etc. Nucleic acid: RNA and DNA

SIZE OF BACTERIA Unit for measurement : Micron or micrometer,μm: 1μm=10-3mm Size: Varies with kinds of bacteria, and also related to their age and external environment

Medical Microbiology and Parasitology Part I: Medical Microbiology Part II: Medical Parasitology

第一节 炎症概述 第二节 急性炎症 第三节 慢性性炎症